Description

4'-Chloro-3'-(Trifluoromethoxy)Acetophenone is a high-purity, synthetically valuable aromatic ketone building block, distinguished by its unique halogenated and trifluoromethoxy substituents. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its structure imparts critical biological activity and metabolic stability. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethoxy group for enhanced efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for creating specialized aromatic cores used in electronic display and lighting technologies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, carbonyl chemistry, and as a scaffold for generating diverse chemical libraries in medicinal chemistry.
• Chemical Research & Development: A vital reagent for academic and industrial research exploring new reaction methodologies and material properties.

Basic Information

Product Name	4'-Chloro-3'-(Trifluoromethoxy)Acetophenone
CAS No.	886501-62-8
Molecular Formula	C9H6ClF3O2
Molecular Weight	238.59 g/mol
Synonyms	1-[4-Chloro-3-(trifluoromethoxy)phenyl]ethanone; 4'-Chloro-3'-(trifluoromethoxy)acetophenone; 4-Chloro-3-trifluoromethoxyacetophenone; 1-(4-Chloro-3-(trifluoromethoxy)phenyl)ethan-1-one; 4-Chloro-α,α,α-trifluoro-m-acetophenone; 3-Trifluoromethoxy-4-chloroacetophenone; Ethanone, 1-[4-chloro-3-(trifluoromethoxy)phenyl]-
EINECS	Contact for details

Quality Control

Our 4'-Chloro-3'-(Trifluoromethoxy)Acetophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.