Description

3-(4-Fluoro-3-(Trifluoromethoxy)Phenyl)Acrylic Acid is a high-value fluorinated aromatic acrylic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring both fluorine and trifluoromethoxy substituents, imparts desirable properties such as enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to construct novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated compounds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated components used in electronic display technologies and organic light-emitting diodes.
• Polymer & Specialty Chemical Modification: Employed to introduce fluorinated phenyl acrylate groups into polymers, enhancing properties like chemical resistance, thermal stability, and surface characteristics.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in medicinal chemistry, material science, and fluorine chemistry.

Basic Information

Product Name	3-(4-Fluoro-3-(Trifluoromethoxy)Phenyl)Acrylic Acid
CAS No.	886501-38-8
Molecular Formula	C10H6F4O3
Molecular Weight	250.15 g/mol
Synonyms	(2E)-3-[4-Fluoro-3-(trifluoromethoxy)phenyl]prop-2-enoic acid; 3-(4-Fluoro-3-(trifluoromethoxy)phenyl)-2-propenoic acid; trans-3-(4-Fluoro-3-(trifluoromethoxy)phenyl)acrylic acid; 4-Fluoro-3-trifluoromethoxycinnamic acid; (E)-3-(4-Fluoro-3-(trifluoromethoxy)phenyl)acrylic acid; 886501-38-8; FTFA (common abbreviation)
EINECS	Contact for details

Quality Control

Our production of 3-(4-Fluoro-3-(Trifluoromethoxy)Phenyl)Acrylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are characterized using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting compliance in regulated R&D and scale-up environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.