Description

4-Chloro-3-(Trifluoromethoxy)Phenylacetic Acid is a high-value fluorinated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring both chloro and trifluoromethoxy substituents, makes it a critical intermediate for developing novel active compounds with enhanced properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting inflammation, metabolic disorders, and central nervous system (CNS) diseases.
• Agrochemical Synthesis: Serves as a versatile precursor in the design and synthesis of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethoxy group.
• Liquid Crystal Materials: Used in the synthesis of advanced fluorinated liquid crystal compounds for high-performance electronic displays.
• Organic Electronics: Acts as a building block for novel organic semiconductors and charge-transport materials due to its electron-withdrawing characteristics.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new chemical reactions, catalytic processes, and material science applications.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical manufacturers for the production of custom-designed molecules and complex intermediates on a commercial scale.

Basic Information

Product Name	4-Chloro-3-(Trifluoromethoxy)Phenylacetic Acid
CAS No.	886501-02-6
Molecular Formula	C9H6ClF3O3
Molecular Weight	254.59 g/mol
Synonyms	2-(4-Chloro-3-(trifluoromethoxy)phenyl)acetic acid; [4-Chloro-3-(trifluoromethoxy)phenyl]acetic Acid; 4-Chloro-α-(trifluoromethoxy)benzeneacetic Acid; 886501-02-6; 4-Chloro-3-trifluoromethoxyphenylacetic acid; (4-Chloro-3-(trifluoromethoxy)phenyl)acetic acid; 2-(4-Chloro-3-(trifluoromethoxy)phenyl)ethanoic acid
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-3-(Trifluoromethoxy)Phenylacetic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against comprehensive specifications using advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.