Description

4-Chloro-3-(Trifluoromethoxy)Benzyl Bromide is a high-value, multi-functional organic building block characterized by its reactive benzyl bromide group and halogenated aromatic ring. This compound is essential for the synthesis of complex molecules, enabling the introduction of the 4-chloro-3-(trifluoromethoxy)benzyl moiety into target structures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of new drugs targeting the central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethoxy group for enhanced biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of novel organic electronic materials, liquid crystals, and polymers with specific electronic or optical properties.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-Chloro-3-(Trifluoromethoxy)Benzyl Bromide
CAS No.	886500-93-2
Molecular Formula	C8H5BrClF3O
Molecular Weight	289.48 g/mol
Synonyms	1-(Bromomethyl)-4-chloro-3-(trifluoromethoxy)benzene; (4-Chloro-3-(trifluoromethoxy)phenyl)methyl bromide; α-Bromo-4-chloro-α-(trifluoromethoxy)toluene; 4-Chloro-α-(bromomethyl)-3-(trifluoromethoxy)benzene; 4-Chloro-3-trifluoromethoxybenzyl bromide
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-3-(Trifluoromethoxy)Benzyl Bromide is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.