Description

4-Pyrrolidin-1-Yl-3-Trifluoromethyl-Benzaldehyde is a high-value, multi-functional aromatic aldehyde building block. This compound matters for its unique structural features, combining a pyrrolidine moiety and a trifluoromethyl group, which are critical for modulating the physicochemical and biological properties of advanced molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance bioavailability and metabolic stability.
• Material Science: Serves as a building block for advanced organic materials, such as ligands for catalysis or monomers for specialty polymers.
• Chemical Synthesis: The aldehyde group is a versatile handle for further functionalization via condensation, reduction, or nucleophilic addition reactions in custom synthesis.
• Academic & Institutional R&D: Employed in universities and research institutes for methodological studies and the exploration of new chemical spaces.

Basic Information

Product Name	4-Pyrrolidin-1-Yl-3-Trifluoromethyl-Benzaldehyde
CAS No.	886500-73-8
Molecular Formula	C₁₂H₁₂F₃NO
Molecular Weight	243.23 g/mol
Synonyms	3-(Trifluoromethyl)-4-(1-pyrrolidinyl)benzaldehyde; 4-(Pyrrolidin-1-yl)-3-(trifluoromethyl)benzaldehyde; 3-Trifluoromethyl-4-pyrrolidin-1-yl-benzaldehyde; 4-Pyrrolidino-3-trifluoromethylbenzaldehyde; 1-[4-Formyl-2-(trifluoromethyl)phenyl]pyrrolidine; Benzaldehyde, 4-(1-pyrrolidinyl)-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 4-Pyrrolidin-1-Yl-3-Trifluoromethyl-Benzaldehyde is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality systems are designed to support cGMP and ISO-guided applications, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.