Description

2,3-Difluoro-4-Methoxybenzamide is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is a critical strategy for modulating biological activity and metabolic stability. It is primarily needed by research institutions and industrial manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and novel materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the difluoro-methoxy motif can enhance efficacy and environmental profile.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and as a precursor for fluorinated materials in advanced chemical research.
• Material Science Research: Acts as a monomer or modifier in the development of specialty polymers and liquid crystals with unique electronic or optical properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific synthesis projects requiring high-purity fluorinated intermediates.

Basic Information

Product Name	2,3-Difluoro-4-Methoxybenzamide
CAS No.	886500-67-0
Molecular Formula	C8H7F2NO2
Molecular Weight	187.14 g/mol
Synonyms	2,3-Difluoro-4-methoxybenzamide; 4-Methoxy-2,3-difluorobenzamide; Benzamide, 2,3-difluoro-4-methoxy-; 2,3-Difluoro-4-methoxy-benzoic acid amide; 886500-67-0; 2,3-Difluoro-4-methoxybenzamide (CAS 886500-67-0); 2,3-Difluoro-p-anisamide
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-Methoxybenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.