Description

n-Methyl-N'-2,2,2-trifluoroethyl ethylenediamine is a specialized fluorinated diamine building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of a reactive ethylenediamine backbone with a trifluoroethyl group, which imparts desirable properties like enhanced lipophilicity and metabolic stability to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals where fluorine substitution is a key design strategy.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in the development of kinase inhibitors, receptor modulators, and other bioactive molecules where the trifluoroethyl group can improve pharmacokinetic properties.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms contribute to increased biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Fluorinated Polymer Research: Employed as a monomer or cross-linking agent in the development of specialty polymers with unique surface, thermal, or chemical resistance properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems, leveraging the fluorine atom for techniques like 19F NMR spectroscopy.
• Fine Chemical and Material Science: Applied in the synthesis of complex fluorinated compounds for electronic materials, liquid crystals, and other high-value specialty chemicals.

Basic Information

Product Name	n-Methyl-N'-2,2,2-trifluoroethyl ethylenediamine
CAS No.	886500-07-8
Molecular Formula	C5H11F3N2
Molecular Weight	156.15 g/mol
Synonyms	N-Methyl-N'-(2,2,2-trifluoroethyl)ethylenediamine; 1-Methyl-2-[(2,2,2-trifluoroethyl)amino]ethane; N1-Methyl-N2-(2,2,2-trifluoroethyl)ethane-1,2-diamine; 2,2,2-Trifluoro-N-(2-(methylamino)ethyl)ethanamine; N-Methyl-N'-(trifluoroethyl)ethylenediamine; 1-Methylamino-2-trifluoroethylaminoethane; TFED; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our n-Methyl-N'-2,2,2-trifluoroethyl ethylenediamine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.