Description

2,3-Difluoro-4-Methoxycinnamic Acid is a high-purity fluorinated cinnamic acid derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the unique reactivity imparted by the strategically positioned fluorine atoms and methoxy group, enabling precise structural modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides with enhanced activity and selectivity.
• Material Science: Serves as a precursor for advanced polymers and liquid crystal materials, leveraging its rigid, fluorinated aromatic structure.
• Chemical Research: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorine Chemistry: Valuable reagent for introducing difluoromethoxy-substituted cinnamate motifs into complex molecules.

Basic Information

Product Name	2,3-Difluoro-4-Methoxycinnamic Acid
CAS No.	886499-79-2
Molecular Formula	C₁₁H₉F₂O₃
Molecular Weight	227.18 g/mol
Synonyms	(2E)-3-(2,3-Difluoro-4-methoxyphenyl)acrylic Acid; (E)-3-(2,3-Difluoro-4-methoxyphenyl)acrylic Acid; 2,3-Difluoro-4-methoxycinnamic Acid; 2,3-Difluoro-4-methoxy-trans-cinnamic Acid; trans-2,3-Difluoro-4-methoxycinnamic Acid; 886499-79-2; 2,3-Difluoro-4-methoxycinnamate
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-Methoxycinnamic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.