Description

2-Methyl-5-(Trifluoromethyl)Benzaldehyde is a versatile fluorinated aromatic aldehyde building block, prized for its unique combination of a reactive formyl group and a stable trifluoromethyl substituent. This compound is essential for introducing lipophilicity and metabolic stability into target molecules, making it a critical intermediate in advanced synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the CF3 group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic electronic materials for displays and lighting applications.
• Functional Dyes & Pigments: Employed in the creation of specialized dyes with altered solubility and spectral properties.
• Cross-Coupling Reactions: Acts as an electrophilic partner in palladium-catalyzed reactions like Suzuki-Miyaura coupling for constructing complex biaryl systems.
• Organic Synthesis Building Block: Used in various condensation, reduction, and nucleophilic addition reactions to introduce the benzaldehyde moiety with enhanced lipophilicity.

Basic Information

Product Name	2-Methyl-5-(Trifluoromethyl)Benzaldehyde
CAS No.	886498-85-7
Molecular Formula	C9H7F3O
Molecular Weight	188.15 g/mol
Synonyms	5-(Trifluoromethyl)-2-methylbenzaldehyde; 2-Methyl-α,α,α-trifluoro-m-tolualdehyde; m-Tolualdehyde, α,α,α-trifluoro-2-methyl-; 2-Methyl-5-trifluoromethylbenzaldehyde; 886498-85-7; 5-(Trifluoromethyl)-o-tolualdehyde; 2-Methyl-5-(trifluoromethyl)benzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(Trifluoromethyl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.