Description

2',6'-Difluoro-4'-Methoxyacetophenone is a high-purity fluorinated acetophenone derivative, a critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which imparts specific electronic and steric properties essential for constructing complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing difluoromethoxy or related aryl-fluorine motifs.
• Agrochemical Synthesis: Used in the research and production of modern pesticides and herbicides, where the fluorine atoms enhance biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and charge-transport materials.
• Chemical Research & Development: A versatile reagent for method development, catalysis studies, and exploring new fluorination reactions in academic and industrial R&D labs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	2',6'-Difluoro-4'-Methoxyacetophenone
CAS No.	886498-84-6
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	1-(2,6-Difluoro-4-methoxyphenyl)ethan-1-one; 2,6-Difluoro-4-methoxyacetophenone; 4'-Methoxy-2',6'-difluoroacetophenone; Ethanone, 1-(2,6-difluoro-4-methoxyphenyl)-; 2,6-Difluoro-4-methoxy-1-acetylbenzene; DFMA; 2,6-Difluoro-4-methoxyacetophenone
EINECS	Contact for details

Quality Control

Our 2',6'-Difluoro-4'-Methoxyacetophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP, ISO, and other relevant regulatory frameworks for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.