Description

2,6-Difluoro-3-Methoxybenzamide is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in its unique substitution pattern, which makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Material Science: Serves as a monomer or additive in the synthesis of specialty polymers and liquid crystals, imparting specific electronic or physical characteristics.
• Chemical Synthesis: Acts as a versatile building block for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex benzamide motifs.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and CROs (Contract Research Organizations) exploring new chemical entities.

Basic Information

Product Name	2,6-Difluoro-3-Methoxybenzamide
CAS No.	886498-26-6
Molecular Formula	C8H7F2NO2
Molecular Weight	187.14 g/mol
Synonyms	3-Methoxy-2,6-difluorobenzamide; 2,6-Difluoro-3-methoxybenzoic acid amide; 2,6-Difluoro-m-anisamide; Benzamide, 2,6-difluoro-3-methoxy-; 886498-26-6; Amide of 2,6-difluoro-3-methoxybenzoic acid
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-Methoxybenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids/bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.