Description

3,4-Difluorobenzylmethylsulfone is a high-purity, functionalized sulfone derivative characterized by its difluorinated benzyl group. This compound serves as a versatile and critical pharmaceutical intermediate and organic synthesis building block, enabling the introduction of specific functional groups into complex molecular architectures. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, where the difluorobenzyl moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of monomers or additives for advanced polymers, liquid crystals, or electronic materials.
• Chemical Biology Probes: Useful for constructing molecular probes to study enzyme mechanisms or protein interactions in biochemical research.
• Custom Synthesis and Contract Manufacturing: A starting material for custom synthesis projects requiring specific fluorinated sulfone functionalities.

Basic Information

Product Name	3,4-Difluorobenzylmethylsulfone
CAS No.	886498-01-7
Molecular Formula	C8H8F2O2S
Molecular Weight	206.21 g/mol
Synonyms	1-(Methylsulfonyl)methyl-3,4-difluorobenzene; (3,4-Difluorophenyl)methyl methyl sulfone; 3,4-Difluoro-α-(methylsulfonyl)toluene; Methyl (3,4-difluorobenzyl) sulfone; 3,4-Difluorobenzyl Methyl Sulfone; α-Methylsulfonyl-3,4-difluorotoluene; 3,4-DFBMS
EINECS	Contact for details

Quality Control

Our 3,4-Difluorobenzylmethylsulfone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for use in sensitive applications like pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.