Description

3'-Chloro-5'-(Trifluoromethyl)Acetophenone is a high-value, multi-functional aromatic ketone building block characterized by its chloro and trifluoromethyl substituents. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its unique halogenated structure imparts critical bioactivity and metabolic stability. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Serves as a crucial precursor for herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced efficacy and environmental profile.
• Ligand and Catalyst Development: Used in organic and organometallic chemistry to create specialized ligands for catalysis and material science applications.
• Fluorinated Compound Research: An important building block in medicinal and materials chemistry for introducing the trifluoromethyl group, which improves lipophilicity and metabolic stability.
• Custom Synthesis and Contract Manufacturing: Supplied to custom synthesis organizations for scale-up and process development of proprietary molecules.

Basic Information

Product Name	3'-Chloro-5'-(Trifluoromethyl)Acetophenone
CAS No.	886497-11-6
Molecular Formula	C9H6ClF3O
Molecular Weight	222.59 g/mol
Synonyms	1-[3-Chloro-5-(trifluoromethyl)phenyl]ethanone; 3-Chloro-5-(trifluoromethyl)acetophenone; 1-(3-Chloro-5-(trifluoromethyl)phenyl)ethan-1-one; 3'-Chloro-α,α,α-trifluoro-m-acetophenone; m-Chloro-α,α,α-trifluoroacetophenone; 3-Chloro-α,α,α-trifluoroacetophenone; 886497-11-6; Ethanone, 1-[3-chloro-5-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 3'-Chloro-5'-(Trifluoromethyl)Acetophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.