Description

4-Bromo-1-Fluoro-2-(Trifluoromethoxy)Benzene 99% is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. Its unique combination of halogen and trifluoromethoxy substituents makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and device performance.
• Polymer & Material Science: Incorporated into specialty polymers and advanced materials to modify thermal stability, chemical resistance, and surface properties.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) due to the reactive bromine atom, enabling complex molecular architecture construction.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new methodologies in fluorination and the development of novel fluorinated compounds.

Basic Information

Product Name	4-Bromo-1-Fluoro-2-(Trifluoromethoxy)Benzene
CAS No.	886496-45-3
Molecular Formula	C7H3BrF4O
Molecular Weight	259.00 g/mol
Synonyms	1-Bromo-4-fluoro-2-(trifluoromethoxy)benzene; 2-Bromo-5-fluoroanisole, 1,1,1-trifluoro-; 4-Bromo-1-fluoro-2-(trifluoromethoxy)benzene; Benzene, 4-bromo-1-fluoro-2-(trifluoromethoxy)-; 886496-45-3; 4-Bromo-alpha,alpha,α-trifluoro-2-fluoroanisole; 2-Bromo-5-fluoro-1-(trifluoromethoxy)benzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Fluoro-2-(Trifluoromethoxy)Benzene 99% is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure it meets the specified 99% minimum purity and is free from critical impurities. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed due to potential moisture sensitivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.