Description

3-Bromo-5-Chloro-4-Fluoro-2-Hydroxy-Benzaldehyde is a highly functionalized benzaldehyde derivative, serving as a critical multi-halogenated building block in advanced organic synthesis. Its unique substitution pattern makes it an invaluable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its halogenated aromatic core.
• Chemical Biology Probes: Serves as a starting material for synthesizing fluorescent tags or molecular probes for diagnostic applications.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing biaryl systems.

Basic Information

Product Name	3-Bromo-5-Chloro-4-Fluoro-2-Hydroxy-Benzaldehyde
CAS No.	886493-35-2
Molecular Formula	C7H3BrClFO2
Molecular Weight	253.45 g/mol
Synonyms	2-Hydroxy-3-bromo-5-chloro-4-fluorobenzaldehyde; 4-Fluoro-2-hydroxy-3-bromo-5-chlorobenzaldehyde; 3-Bromo-5-chloro-4-fluoro-2-hydroxybenzaldehyde; 886493-35-2; 5-Chloro-3-bromo-4-fluoro-2-hydroxybenzaldehyde; 4-Fluoro-2-hydroxy-5-chloro-3-bromobenzaldehyde; Benzaldehyde, 3-bromo-5-chloro-4-fluoro-2-hydroxy-
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chloro-4-Fluoro-2-Hydroxy-Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.