Description

1-(2,3-Dichloro-Phenyl)-2,2,2-Trifluoro-Ethanone is a high-purity, specialty fluorinated aromatic ketone building block. This compound is a critical intermediate in advanced organic synthesis, valued for its unique trifluoroacetyl and dichlorophenyl functional groups which enable precise molecular modifications. It is primarily required by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethyl ketone or dichlorophenyl pharmacophores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the dichloro and trifluoro motifs enhance biological activity and stability.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials with tailored properties.
• Organic Synthesis Reagent: Employed in Friedel-Crafts acylation and other reactions to introduce the 2,3-dichlorophenyl-trifluoroacetyl moiety into complex molecular architectures.
• Chemical Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	1-(2,3-Dichloro-Phenyl)-2,2,2-Trifluoro-Ethanone
CAS No.	886371-11-5
Molecular Formula	C8H3Cl2F3O
Molecular Weight	243.01 g/mol
Synonyms	2,3-Dichloro-α,α,α-trifluoroacetophenone; 2',3'-Dichloro-2,2,2-trifluoroacetophenone; 1-(2,3-Dichlorophenyl)-2,2,2-trifluoroethanone; 2,3-Dichlorophenyl trifluoromethyl ketone; (2,3-Dichlorophenyl)(trifluoromethyl)methanone; TFAP-DC; α,α,α-Trifluoro-2,3-dichloroacetophenone
EINECS	Contact for details

Quality Control

Our 1-(2,3-Dichloro-Phenyl)-2,2,2-Trifluoro-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports cGMP and ISO standards for reliable integration into regulated synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.