Description

1-(2,4-Difluoro-Phenyl)-2,2,2-Trifluoro-Ethanone is a high-purity fluorinated aromatic ketone building block. This compound is valued for its unique trifluoroacetyl group and difluorophenyl ring, which are critical for imparting specific electronic and steric properties in advanced molecular synthesis. It is primarily sought by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Building Block: Used in the research and production of advanced herbicides and fungicides, where the fluorine atoms enhance bioavailability and environmental stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and liquid crystals with tailored optical and thermal properties.
• Organic Synthesis Reagent: Employed in Friedel-Crafts acylation and other reactions to introduce the trifluoroacetyl moiety into complex organic molecules.
• Fluorine Chemistry Research: An essential compound for academic and industrial research exploring the effects of fluorine substitution on molecular reactivity and physical characteristics.

Basic Information

Product Name	1-(2,4-Difluoro-Phenyl)-2,2,2-Trifluoro-Ethanone
CAS No.	886371-05-7
Molecular Formula	C8H3F5O
Molecular Weight	210.10 g/mol
Synonyms	2',4'-Difluoro-2,2,2-trifluoroacetophenone; 2,4-Difluorophenyl Trifluoromethyl Ketone; 1-(2,4-Difluorophenyl)-2,2,2-trifluoroethanone; α,α,α-Trifluoro-2',4'-difluoroacetophenone; 2,2,2-Trifluoro-1-(2,4-difluorophenyl)ethanone; TFAP-2,4-diF; DFTA
EINECS	Contact for details

Quality Control

Every batch of 1-(2,4-Difluoro-Phenyl)-2,2,2-Trifluoro-Ethanone is manufactured under a strict quality management system. We provide comprehensive analytical documentation to ensure traceability and compliance with your project requirements. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider using an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.