Description

1-(4-Methylnaphthyl) Trifluoromethyl Ketone is a high-purity, specialized organic intermediate featuring a naphthalene backbone substituted with a trifluoromethyl ketone group. This compound is valued for its unique electronic properties and structural rigidity, making it a critical building block in advanced chemical synthesis. It is primarily sought by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers and liquid crystals with tailored optical and electronic properties.
• Organic Synthesis: Employed in palladium-catalyzed cross-coupling reactions and as a substrate for nucleophilic addition reactions to construct complex molecular architectures.
• Fluorine Chemistry: A valuable reagent for introducing the trifluoromethylacetyl moiety into target molecules, a group known to improve metabolic stability and lipophilicity.

Basic Information

Product Name	1-(4-Methylnaphthyl) Trifluoromethyl Ketone
CAS No.	886370-33-8
Molecular Formula	C₁₃H₉F₃O
Molecular Weight	238.21 g/mol
Synonyms	1-(4-Methyl-1-naphthyl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(4-methyl-1-naphthyl)ethanone; 4-Methyl-1-naphthyl trifluoromethyl ketone; 1-(4-Methylnaphthalen-1-yl)-2,2,2-trifluoroethanone; TFMK-4MN; 886370-33-8 (CAS Registry)
EINECS	Contact for details

Quality Control

Our 1-(4-Methylnaphthyl) Trifluoromethyl Ketone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the exacting standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.