Description

1-(2,3-Dimethyl-Phenyl)-2,2,2-Trifluoro-Ethanone is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in the trifluoroacetyl group, which introduces unique electronic and steric properties, enabling the development of novel compounds with enhanced metabolic stability and bioavailability. This high-purity intermediate is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to create active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of molecules containing trifluoromethyl groups for improved drug-like properties.
• Agrochemical Synthesis: Used in the research and manufacture of advanced pesticides and herbicides, where the fluorine atoms contribute to increased efficacy and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials that require specific optical or electronic characteristics.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory testing in industrial laboratories.

Basic Information

Product Name	1-(2,3-Dimethyl-Phenyl)-2,2,2-Trifluoro-Ethanone
CAS No.	886369-37-5
Molecular Formula	C10H9F3O
Molecular Weight	202.17 g/mol
Synonyms	2,3-Dimethyl-α,α,α-trifluoroacetophenone; 2',3'-Dimethyl-2,2,2-trifluoroacetophenone; 1-(2,3-Dimethylphenyl)-2,2,2-trifluoroethanone; 2,3-Dimethyltrifluoroacetophenone; α,α,α-Trifluoro-2,3-dimethylacetophenone; TFAP derivative (2,3-dimethyl); (2,3-Dimethylphenyl) trifluoromethyl ketone
EINECS	Contact for details

Quality Control

Our 1-(2,3-Dimethyl-Phenyl)-2,2,2-Trifluoro-Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.