Description

1-(4-tert-Butylphenyl)-2,2,2-Trifluoroethan-1-Amine is a high-value, fluorinated aromatic amine building block. This compound is essential for the synthesis of advanced materials and active pharmaceutical ingredients (APIs) due to the unique electronic and steric properties imparted by the tert-butyl and trifluoromethyl groups. It is primarily utilized by research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral precursor for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a backbone for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and organic electronic materials to modify solubility and electronic properties.
• Chemical Biology Probes: Acts as a building block for fluorescent tags and molecular probes used in diagnostic and imaging applications.

Basic Information

Product Name	1-(4-tert-Butylphenyl)-2,2,2-Trifluoroethan-1-Amine
CAS No.	886369-21-7
Molecular Formula	C12H16F3N
Molecular Weight	231.26 g/mol
Synonyms	α-(Trifluoromethyl)-4-tert-butylbenzylamine; 1-(4-(tert-Butyl)phenyl)-2,2,2-trifluoroethanamine; 4-tert-Butyl-α-(trifluoromethyl)benzylamine; 1-(4-tert-Butylphenyl)-2,2,2-trifluoroethylamine; (4-tert-Butylphenyl)(trifluoromethyl)methylamine; p-tert-Butyl-α-trifluoromethylbenzylamine; 886369-21-7; 1-(4-tert-butylphenyl)-2,2,2-trifluoroethan-1-amine
EINECS	Contact for details

Quality Control

Our 1-(4-tert-Butylphenyl)-2,2,2-Trifluoroethan-1-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP, ICH Q7 guidelines, and relevant global regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Chiral Purity (Chiral HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.