Description

2-Biphenyl-3',4'-Difluoro-Carboxylic Acid is a high-purity, multi-functional biphenyl derivative featuring strategically placed fluorine atoms and a carboxylic acid group. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern organic synthesis, prized for its ability to impart specific electronic and steric properties to target molecules. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic display materials due to its rigid biphenyl core and fluorine substitution.
• Polymer Chemistry: Acts as a monomer or functionalizing agent for creating specialty polymers with tailored thermal and chemical resistance properties.
• Organic Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A valuable tool for medicinal chemistry and process chemistry in exploring new molecular entities and optimizing synthetic routes.

Basic Information

Product Name	2-Biphenyl-3',4'-Difluoro-Carboxylic Acid
CAS No.	886363-30-0
Molecular Formula	C13H8F2O2
Molecular Weight	234.20 g/mol
Synonyms	[1,1'-Biphenyl]-2-carboxylic acid, 3',4'-difluoro-; 3',4'-Difluoro[1,1'-biphenyl]-2-carboxylic acid; 2-(3',4'-Difluorobiphenyl-2-yl)carboxylic acid; 3',4'-Difluoro-2-biphenylcarboxylic acid; 2-Carboxy-3',4'-difluorobiphenyl; 3',4'-Difluorobiphenyl-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Biphenyl-3',4'-Difluoro-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable batch-to-batch consistency for your development and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.