Description

2-Amino-5-(3-Fluorophenyl)-1,3-Thiazole-4-Carbohydrazide is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique thiazole-hydrazide scaffold enables the creation of targeted bioactive molecules. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, particularly in the synthesis of kinase inhibitors and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and anti-cancer agents.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the bioactivity of the thiazole core.
• Chemical Biology Probe Synthesis: Serves as a building block for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and novel heterocycle synthesis.

Basic Information

Product Name	2-Amino-5-(3-Fluorophenyl)-1,3-Thiazole-4-Carbohydrazide
CAS No.	886361-60-0
Molecular Formula	C10H9FN4OS
Molecular Weight	252.27 g/mol
Synonyms	2-Amino-5-(3-fluorophenyl)-1,3-thiazole-4-carboxylic acid hydrazide; 5-(3-Fluorophenyl)-2-amino-1,3-thiazole-4-carbohydrazide; 4-Hydrazinylcarbonyl-5-(3-fluorophenyl)-1,3-thiazol-2-amine; 2-Amino-5-(3-fluorophenyl)-4-thiazolecarbohydrazide; 886361-60-0; AKOS006361602; FT-0777689; EN300-1311867.
EINECS	Contact for details

Quality Control

Our 2-Amino-5-(3-Fluorophenyl)-1,3-Thiazole-4-Carbohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with research and development grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.