Description

2,3,5,6-Tetrafluoro-Benzamidine is a high-value fluorinated benzamidine derivative, a key building block in advanced organic synthesis. Its unique perfluorinated aromatic core makes it an essential precursor for developing novel pharmaceuticals and agrochemicals with enhanced metabolic stability and bioavailability. This compound is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of protease inhibitors, kinase inhibitors, and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorine atoms confer improved lipophilicity and target binding.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials for their unique electronic properties.
• Chemical Biology Probes: Utilized in the design of activity-based probes and diagnostic agents due to its amidine functionality.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects requiring the introduction of a fluorinated benzamidine moiety.

Basic Information

Product Name	2,3,5,6-Tetrafluoro-Benzamidine
CAS No.	885954-80-3
Molecular Formula	C7H4F4N2
Molecular Weight	192.12 g/mol
Synonyms	2,3,5,6-Tetrafluorobenzamidine; Benzamidine, 2,3,5,6-tetrafluoro-; 2,3,5,6-Tetrafluorobenzenecarboximidamide; Tetrafluorobenzamidine; Perfluorobenzamidine (common name); 885954-80-3 (CAS); TFBAmidine
EINECS	Contact for details

Quality Control

Every batch of 2,3,5,6-Tetrafluoro-Benzamidine is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and custom specifications can be developed to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.