Description

3-[5-(4-Chloro-Phenyl)-1,3,4-Thiadiazol-2-Yl]-Propionic Acid Methyl Ester is a high-value synthetic intermediate characterized by its unique thiadiazole core linked to a chlorophenyl group and a propionate ester. This compound matters for its role as a versatile building block in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its specific structure enables targeted molecular design. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing new compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzymes or receptors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging the bioactivity of the thiadiazole moiety.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for constructing more complex heterocyclic compounds in medicinal and organic chemistry.
• Material Science Research: Potential intermediate for creating specialized polymers or organic electronic materials with specific properties.
• Biochemical Tool Compound: May be used in academic and industrial research to study biological pathways or as a probe in assay development.

Basic Information

Product Name	3-[5-(4-Chloro-Phenyl)-1,3,4-Thiadiazol-2-Yl]-Propionic Acid Methyl Ester
CAS No.	885951-43-9
Molecular Formula	C₁₂H₁₁ClN₂O₂S
Molecular Weight	282.74 g/mol
Synonyms	Methyl 3-[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]propanoate; 3-(5-(4-Chlorophenyl)-1,3,4-thiadiazol-2-yl)propionic acid methyl ester; Methyl 3-(5-(p-chlorophenyl)-1,3,4-thiadiazol-2-yl)propionate; 4-Chloro-α-(5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl)benzenepropanoic acid methyl ester (related); 885951-43-9; Thiadiazole propionate ester intermediate
EINECS	Contact for details

Quality Control

Our 3-[5-(5-(4-Chloro-Phenyl)-1,3,4-Thiadiazol-2-Yl]-Propionic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.