Description

1-(4-[(2-Bromo-5-Methoxybenzyl)Oxy]-3-Fluorophenyl)-1-Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated and ether-linked aromatic structure. This compound matters for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in research areas targeting neurological and oncological pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new molecular entities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those with fluorinated and brominated aromatic systems.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides where the methoxybenzyl moiety can impart specific biological activity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and etherification processes to construct more complex molecular architectures.
• Material Science Research: Investigated as a monomer or additive in the development of specialty polymers and advanced organic materials.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	1-(4-[(2-Bromo-5-Methoxybenzyl)Oxy]-3-Fluorophenyl)-1-Ethanone
CAS No.	885949-81-5
Molecular Formula	C₁₆H₁₄BrFO₃
Molecular Weight	353.19 g/mol
Synonyms	1-[4-[(2-Bromo-5-methoxybenzyl)oxy]-3-fluorophenyl]ethanone; 2-Bromo-5-methoxybenzyl 3-fluoro-4-acetylphenyl ether; 4'-Acetyl-2'-fluoro-4-[(2-bromo-5-methoxybenzyl)oxy]benzene; 3-Fluoro-4-[(2-bromo-5-methoxybenzyl)oxy]acetophenone; 1-(3-Fluoro-4-{[ (2-bromo-5-methoxyphenyl)methyl]oxy}phenyl)ethan-1-one; CAS 885949-81-5
EINECS	Contact for details

Quality Control

Our 1-(4-[(2-Bromo-5-Methoxybenzyl)Oxy]-3-Fluorophenyl)-1-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.