Description

2-Methyl-2H-Indazole-4-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. Its core value lies in its role as a protected boronic acid derivative, offering enhanced stability and handling properties for critical cross-coupling reactions. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality reagents for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable organoboron reagent for forming carbon-carbon bonds to construct complex aromatic and heteroaromatic systems.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors and light-emitting materials for electronic devices.
• Chemical Biology & Probe Development: Utilized for creating molecular probes and labeled compounds for biological target identification.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring indazole-based molecular frameworks.

Basic Information

Item	Details
Product Name	2-Methyl-2H-Indazole-4-Boronic Acid Pinacol Ester
CAS No.	885698-95-3
Molecular Formula	C14H19BN2O2
Molecular Weight	258.13 g/mol
Synonyms	2-Methyl-2H-indazol-4-ylboronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methyl-2H-indazole; 2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-indazole; 2-Methyl-2H-indazole-4-boronic acid, pinacol ester; Boronic acid, B-(2-methyl-2H-indazol-4-yl)-, 1,1,1',1'-tetramethyl-2,2'-bi-1,3,2-dioxaborolane ester; 885698-95-3
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-2H-Indazole-4-Boronic Acid Pinacol Ester is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and LC-MS to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.