Description

1-Methyl-1H-Indazole-4-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and a key building block in modern synthetic chemistry. Its value lies in its role as a protected boronic acid derivative, offering enhanced stability and handling characteristics for critical coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients through Suzuki-Miyaura cross-coupling.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of complex drug candidates, especially those containing the indazole heterocycle.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable organoboron reagent for forming carbon-carbon bonds in medicinal chemistry and material science research.
• Agrochemical Research: Used in the development of new pesticides and herbicides that require specific heterocyclic architectures.
• Material Science: A precursor for creating organic electronic materials and functional polymers.
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Employed in the construction of bifunctional molecules for targeted protein degradation.
• Contract Research & Development (CRO/CDMO): Supplied to research organizations for custom synthesis and process development projects.

Basic Information

Product Name	1-Methyl-1H-Indazole-4-Boronic Acid Pinacol Ester
CAS No.	885698-94-2
Molecular Formula	C₁₄H₁₉BN₂O₂
Molecular Weight	258.13 g/mol
Synonyms	1-Methyl-1H-indazol-4-ylboronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-methyl-1H-indazole; 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole; B-(1-Methyl-1H-indazol-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1-Methylindazole-4-boronic acid pinacol ester; 885698-94-2; 1-Methyl-4-(pinacolboronato)indazole
EINECS	Contact for details

Quality Control

Our 1-Methyl-1H-Indazole-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed under an inert atmosphere to maintain long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.