Description

Methyl [3-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane-2-Yl)Phenyl]Acetate is a high-purity boronic ester derivative, a critical synthetic intermediate in modern organic and medicinal chemistry. Its value lies in its stability and reactivity, making it an essential building block for constructing complex molecular architectures through cross-coupling reactions. This compound is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, enabling the introduction of the biaryl moiety essential for biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the synthesis of chemical probes and affinity tags for studying protein function and interaction networks.
• Ligand & Catalyst Development: Acts as a starting material for synthesizing novel bidentate ligands and organometallic catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A vital component for CROs and CDMOs offering bespoke chemical synthesis services for client-specific projects.

Basic Information

Product Name	Methyl [3-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane-2-Yl)Phenyl]Acetate
CAS No.	885681-94-7
Molecular Formula	C₁₈H₂₇BO₄
Molecular Weight	318.22 g/mol
Synonyms	2-[4-(Methoxycarbonylmethyl)-2-methylphenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Methyl 2-[3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetate; [3-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetic acid methyl ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-m-tolylacetic acid methyl ester; Pinacol ester of Methyl (3-Methyl-4-boronophenyl)acetate; Methyl 3-Methyl-4-(pinacolatoboron)benzylacetate
EINECS	Contact for details

Quality Control

Our Methyl [3-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane-2-Yl)Phenyl]Acetate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization, including NMR, HPLC, and GC, to ensure identity, purity, and lot-to-lot consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥96.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.