Description

2-Phenyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Oxazole is a high-value, heterocyclic boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon and carbon-heteroatom bond formation via the versatile Suzuki-Miyaura cross-coupling reaction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for constructing complex molecular architectures. The CAS number for this compound is 885669-16-9.

Application

This specialized boronic ester is a key intermediate in the synthesis of complex organic molecules. Its primary applications include:

• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for constructing biaryl and heteroaryl motifs common in drug candidates.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs and components for organic semiconductors.
• Chemical Research: A versatile reagent in academic and industrial R&D for methodology development and library synthesis in medicinal and process chemistry.
• Ligand & Catalyst Preparation: Used to synthesize complex ligands for transition metal catalysts.

Basic Information

Item	Details
Product Name	2-Phenyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Oxazole
CAS No.	885669-16-9
Molecular Formula	C15H18BNO3
Molecular Weight	271.12 g/mol
Synonyms	2-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-oxazole; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-phenyloxazole; 2-Phenyloxazole-4-boronic acid pinacol ester; Oxazole-4-boronic acid, 2-phenyl-, pinacol ester; 885669-16-9; PINACOL 2-PHENYLOXAZOLE-4-BORONATE
EINECS	Contact for details

Quality Control

Our 2-Phenyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Oxazole is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the product should be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.