Description

1-Boc-4-Ethyl-4-(Hydroxymethyl)-Piperidine is a versatile and high-purity piperidine derivative, serving as a critical protected intermediate in advanced organic synthesis. Its value lies in the orthogonal protection of the piperidine nitrogen by the Boc (tert-butoxycarbonyl) group and the presence of a hydroxymethyl handle, enabling precise and sequential chemical modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors who require reliable building blocks for developing active pharmaceutical ingredients (APIs) and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides due to its functionalized piperidine core.
• Peptidomimetics & Molecular Scaffolds: Employed in medicinal chemistry to create constrained peptide analogs and three-dimensional molecular scaffolds.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Custom Chemical Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for clients.
• Academic & R&D Laboratories: Used in fundamental research exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	1-Boc-4-Ethyl-4-(Hydroxymethyl)-Piperidine
CAS No.	885523-38-6
Molecular Formula	C13H25NO3
Molecular Weight	243.34 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-4-ethyl-4-(hydroxymethyl)piperidine; 4-Ethyl-4-(hydroxymethyl)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-ethyl-4-(hydroxymethyl)piperidine-1-carboxylate; 1-Boc-4-ethyl-4-piperidinemethanol; N-Boc-4-ethyl-4-(hydroxymethyl)piperidine; 4-(Hydroxymethyl)-4-ethylpiperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1-Boc-4-Ethyl-4-(Hydroxymethyl)-Piperidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistent identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.