Description

4-Fluoro-6-Methyl-3-(1H)Indazole Carboxaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique indazole core functionalized with fluorine and aldehyde groups. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel, targeted drug candidates. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors, oncology therapeutics, and other small-molecule drugs where its specific scaffold provides key structural and electronic properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent kinase inhibitors and other targeted cancer therapies.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies for novel drug discovery.
• Organic Synthesis Building Block: The reactive aldehyde group facilitates further derivatization through condensation, reductive amination, and other coupling reactions.
• Agrochemical Development: Serves as a starting material for creating new active ingredients with enhanced biological activity.
• Material Science Research: Investigated for the development of specialty chemicals and functional materials.

Basic Information

Product Name	4-Fluoro-6-Methyl-3-(1H)Indazole Carboxaldehyde
CAS No.	885522-22-5
Molecular Formula	C10H7FN2O
Molecular Weight	190.18 g/mol
Synonyms	4-Fluoro-6-methyl-1H-indazole-3-carbaldehyde; 4-Fluoro-6-methyl-1H-indazole-3-carboxaldehyde; 6-Methyl-4-fluoro-1H-indazole-3-carboxaldehyde; 3-Formyl-4-fluoro-6-methyl-1H-indazole; 4-Fluoro-6-methylindazole-3-carboxaldehyde; 4-Fluoro-6-methyl-3-indazolecarboxaldehyde; 885522-22-5
EINECS	Contact for details

Quality Control

Our 4-Fluoro-6-Methyl-3-(1H)Indazole Carboxaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.