Description

3-Bromo-4-Fluoro-6-Indazolecarboxylic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique halogenated indazole structure makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of kinase inhibitors, anticancer agents, and other small molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated indazole core.
• Material Science: Serves as a precursor for functionalized ligands and monomers in the creation of specialty polymers and advanced organic materials.
• Chemical Biology & Proteomics: Employed as a scaffold for designing molecular probes and activity-based protein profiling (ABPP) reagents.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis and library production for high-throughput screening.

Basic Information

Product Name	3-Bromo-4-Fluoro-6-Indazolecarboxylic Acid
CAS No.	885521-65-3
Molecular Formula	C8H4BrFN2O2
Molecular Weight	259.03 g/mol
Synonyms	3-Bromo-4-fluoro-1H-indazole-6-carboxylic acid; 4-Fluoro-3-bromo-1H-indazole-6-carboxylic acid; 6-Indazolecarboxylic acid, 3-bromo-4-fluoro-; 885521-65-3; 3-Bromo-4-fluoroindazole-6-carboxylic acid; 3-Br-4-F-6-ICA
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-4-Fluoro-6-Indazolecarboxylic Acid is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥97% (HPLC), with options for higher grades (≥98%, ≥99%) available. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical characteristics is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.