Description

4-Amino-3-Iodo-6-Indazolecarboxylic Acid Methyl Ester is a high-purity, functionalized indazole derivative serving as a critical synthetic intermediate. Its value lies in providing a versatile scaffold for constructing complex molecules in advanced research and development. This compound is primarily needed by pharmaceutical and agrochemical R&D teams for applications in medicinal chemistry and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• Agrochemical Development: Serves as a precursor in the creation of new herbicides, fungicides, or plant growth regulators.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Organic Synthesis: Valuable intermediate for further functionalization, including cross-coupling reactions, due to the reactive iodo and amino groups.
• Material Science Research: Potential precursor for specialty chemicals and advanced functional materials.

Basic Information

Product Name	4-Amino-3-Iodo-6-Indazolecarboxylic Acid Methyl Ester
CAS No.	885521-05-1
Molecular Formula	C9H8IN3O2
Molecular Weight	317.09 g/mol
Synonyms	Methyl 4-Amino-3-Iodo-1H-indazole-6-carboxylate; 4-Amino-3-iodo-1H-indazole-6-carboxylic acid methyl ester; 6-Indazolecarboxylic acid, 4-amino-3-iodo-, methyl ester; 885521-05-1; 4-Amino-3-iodo-6-(methoxycarbonyl)-1H-indazole; Methyl 4-amino-3-iodo-6-indazolecarboxylate
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Iodo-6-Indazolecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and tendency for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.