Description

2-(2,2,3,3-Tetrafluorocyclobutyl)Acetic Acid is a high-value, fluorinated organic acid building block characterized by its unique cyclobutane ring structure. This compound is essential for introducing tetrafluorocyclobutyl motifs into target molecules, significantly altering their physicochemical properties. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly those requiring enhanced metabolic stability, lipophilicity, or bioavailability.
• Agrochemical Research: Used in creating advanced herbicides, fungicides, and insecticides where the fluorinated cyclobutyl group can improve activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Incorporated as a monomer or cross-linking agent to produce specialty fluoropolymers with unique thermal and chemical resistance.
• Advanced Material Science: Employed in the research and development of coatings, surfactants, and other performance chemicals that benefit from fluorine's properties.
• Chemical Synthesis Building Block: Utilized in organic synthesis for further derivatization, including esterification, amidation, and reduction reactions.

Basic Information

Item	Detail
Product Name	2-(2,2,3,3-Tetrafluorocyclobutyl)Acetic Acid
CAS No.	885459-27-8
Molecular Formula	C6H6F4O2
Molecular Weight	186.11 g/mol
Synonyms	2-(Perfluorocyclobutyl)acetic acid (common name); 2-(Tetrafluorocyclobutyl)acetic acid; Acetic acid, 2-(2,2,3,3-tetrafluorocyclobutyl)-; 885459-27-8; Tetrafluorocyclobutaneacetic acid; 2-(2,2,3,3-Tetrafluorocyclobut-1-yl)acetic acid; Perfluorocyclobutylacetic acid; FCBA (abbreviation)
EINECS	Contact for details

Quality Control

Every batch of 2-(2,2,3,3-Tetrafluorocyclobutyl)Acetic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data including HPLC purity, NMR, and MS to verify identity and quality. Certificates of Analysis (COA) documenting all critical parameters are available upon request for your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizers, and sources of ignition. Due to its acidic nature, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.