Description

4-Cyclobutyl-3-Oxo-Butyric Acid Ethyl Ester is a versatile β-keto ester building block, prized for its reactive carbonyl and ester functionalities. This compound is essential for facilitating complex organic syntheses, particularly in the construction of cyclic and heterocyclic frameworks. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules, especially those containing cyclobutane or modified β-keto acid motifs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other high-value specialty chemicals.
• Organic Synthesis Research: A valuable reagent for Claisen condensations, Michael additions, and other C-C bond-forming reactions in academic and industrial R&D.
• Material Science: Potential monomer or cross-linking agent in the development of novel polymers with specific thermal or mechanical properties.

Basic Information

Product Name	4-Cyclobutyl-3-Oxo-Butyric Acid Ethyl Ester
CAS No.	885280-12-6
Molecular Formula	C10H16O3
Molecular Weight	184.23 g/mol
Synonyms	Ethyl 4-Cyclobutyl-3-oxobutanoate; 3-Oxo-4-cyclobutylbutyric Acid Ethyl Ester; Ethyl 4-Cyclobutylacetoacetate; 4-Cyclobutylacetoacetic Acid Ethyl Ester; Butanoic acid, 4-cyclobutyl-3-oxo-, ethyl ester; 885280-12-6; Ethyl (4-cyclobutyl-3-oxobutanoate)
EINECS	Contact for details

Quality Control

Our 4-Cyclobutyl-3-Oxo-Butyric Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications from GC, HPLC, and NMR are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.