Description

6-Fluoro-1H-Benzoimidazole-2-Carboxylic Acid Methyl Ester is a high-value fluorinated benzimidazole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in enabling the precise construction of complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and material science industries who require a reliable, high-purity building block for heterocyclic synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting oncology, antiviral, and central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel fungicides and herbicides, where the fluorine atom and benzimidazole core enhance biological activity and stability.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs) in material science.
• Fluorescent Probe Development: Serves as a building block for creating fluorophore-labeled compounds used in biochemical assays and diagnostic imaging.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and process research in academic institutions and CROs/CDMOs.

Basic Information

Product Name	6-Fluoro-1H-Benzoimidazole-2-Carboxylic Acid Methyl Ester
CAS No.	885280-04-6
Molecular Formula	C9H7FN2O2
Molecular Weight	194.16 g/mol
Synonyms	Methyl 6-Fluoro-1H-benzimidazole-2-carboxylate; 6-Fluoro-1H-benzo[d]imidazole-2-carboxylic acid methyl ester; 6-Fluoro-1H-benzimidazole-2-carboxylic acid methyl ester; 6-Fluorobenzimidazole-2-carboxylic acid methyl ester; 885280-04-6; Methyl 6-fluorobenzimidazole-2-carboxylate; 6-Fluoro-2-(methoxycarbonyl)-1H-benzimidazole
EINECS	Contact for details

Quality Control

Our production of 6-Fluoro-1H-Benzoimidazole-2-Carboxylic Acid Methyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and MS. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon to preserve stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.