Description

3-(3-Fluoro-Phenyl)-Isoxazole-5-Carbaldehyde is a high-purity fluorinated isoxazole derivative, a crucial building block in modern organic synthesis. This compound matters for its role as a versatile precursor in the development of novel pharmaceuticals and agrochemicals, enabling the introduction of key structural motifs. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the isoxazole and fluorophenyl groups.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials requiring fluorinated aromatic systems.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways due to its reactive aldehyde group for bioconjugation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects and scale-up campaigns.

Basic Information

Product Name	3-(3-Fluoro-Phenyl)-Isoxazole-5-Carbaldehyde
CAS No.	885273-52-9
Molecular Formula	C10H6FNO2
Molecular Weight	191.16 g/mol
Synonyms	3-(3-Fluorophenyl)-1,2-oxazole-5-carbaldehyde; 5-Formyl-3-(3-fluorophenyl)isoxazole; 3-(3-Fluorophenyl)-5-isoxazolecarboxaldehyde; 885273-52-9; 3-(3-Fluorophenyl)isoxazole-5-carbaldehyde; 3-(m-Fluorophenyl)isoxazole-5-carboxaldehyde; AI3-52099
EINECS	Contact for details

Quality Control

Every batch of 3-(3-Fluoro-Phenyl)-Isoxazole-5-Carbaldehyde is produced and tested under strict quality management systems. We ensure compliance with relevant industry standards for advanced intermediates. Comprehensive analytical testing, including HPLC, GC, NMR, and MS, is performed to guarantee identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.