Description

5-(Aminomethyl)-2,3-Dihydro-1H-Inden-1-Ol is a versatile chiral amino alcohol building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and fine chemicals, offering a rigid indane scaffold with both amino and hydroxyl functional groups for selective derivatization. Pharmaceutical researchers, agrochemical developers, and specialty chemical manufacturers need it to create novel compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for creating advanced pesticides and herbicides with enhanced efficacy and selectivity.
• Ligand and Catalyst Preparation: Used in the synthesis of chiral ligands for asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals for various industrial applications.
• Academic and R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research within university and corporate laboratories.

Basic Information

Product Name	5-(Aminomethyl)-2,3-Dihydro-1H-Inden-1-Ol
CAS No.	885272-06-0
Molecular Formula	C10H13NO
Molecular Weight	163.22 g/mol
Synonyms	1H-Inden-1-ol, 5-(aminomethyl)-2,3-dihydro-; (1S)-5-(Aminomethyl)-2,3-dihydro-1H-inden-1-ol (enantiomer); 5-(Aminomethyl)indan-1-ol; 1-Amino-2,3-dihydro-1H-inden-5-ylmethanol; Aminoindanol derivative; CAS 885272-06-0
EINECS	Contact for details

Quality Control

Our 5-(Aminomethyl)-2,3-Dihydro-1H-Inden-1-Ol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.