Description

5-Trifluoromethyl-1-Tetralone is a high-value fluorinated organic intermediate characterized by its tetralone core structure substituted with a trifluoromethyl group. This compound is prized for its role as a versatile building block in advanced organic synthesis, where the CF₃ group imparts unique physicochemical properties to target molecules. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science: Used in the research and development of specialty polymers and liquid crystals where fluorine incorporation modifies thermal and optical properties.
• Organic Synthesis: A versatile synthon for constructing complex polycyclic frameworks and introducing the trifluoromethyl group via further functionalization.
• Chemical Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	5-Trifluoromethyl-1-Tetralone
CAS No.	885268-02-0
Molecular Formula	C₁₁H₉F₃O
Molecular Weight	214.19 g/mol
Synonyms	5-(Trifluoromethyl)-3,4-dihydronaphthalen-1(2H)-one; 1-Tetralone, 5-(trifluoromethyl)-; 5-(Trifluoromethyl)-1-tetralone; 5-Trifluoromethyl-3,4-dihydro-1(2H)-naphthalenone; 5-Trifluoromethyl-3,4-dihydronaphthalen-1(2H)-one; 5-Trifluoromethyl-α-tetralone
EINECS	Contact for details

Quality Control

Our 5-Trifluoromethyl-1-Tetralone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.