Description

3-Fluoro-6-Bromo-2-Pyridinecarboxaldehyde is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an indispensable precursor for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its halogenated pyridine core for bioactivity.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating sophisticated chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the research and development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology: Utilized as a probe or labeling agent due to its reactive aldehyde group, which can form covalent bonds with amines.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to build complex biaryl systems.

Basic Information

Item	Detail
Product Name	3-Fluoro-6-Bromo-2-Pyridinecarboxaldehyde
CAS No.	885267-36-7
Molecular Formula	C6H3BrFNO
Molecular Weight	203.99 g/mol
Synonyms	6-Bromo-3-fluoro-2-pyridinecarboxaldehyde; 2-Bromo-5-fluoropyridine-6-carbaldehyde; 3-Fluoro-6-bromopicolinaldehyde; 6-Bromo-3-fluoropicolinaldehyde; 2-Pyridinecarboxaldehyde, 3-fluoro-6-bromo-; 885267-36-7; 3-Fluoro-6-bromopyridine-2-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-6-Bromo-2-Pyridinecarboxaldehyde is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity, the material should be handled under an inert atmosphere to prevent oxidation and stored away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.