Description

3-Methyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carbaldehyde is a high-purity heterocyclic aldehyde building block of significant importance in advanced organic synthesis. This compound matters as a versatile and critical precursor for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). Pharmaceutical R&D laboratories and fine chemical manufacturers need it for creating targeted drug candidates, especially in therapeutic areas requiring sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug molecules, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and herbicides that require specific pyrazolopyridine scaffolds.
• Material Science Research: Serves as a building block for organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and diagnostic agents for studying biological pathways.
• Academic & Industrial R&D: Essential for methodological development in organic chemistry and for scaling novel synthetic routes.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	3-Methyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carbaldehyde
CAS No.	885223-66-5
Molecular Formula	C8H7N3O
Molecular Weight	161.16 g/mol
Synonyms	3-Methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxaldehyde; 5-Formyl-3-methyl-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine-5-carboxaldehyde, 3-methyl-; 3-Methyl-1H-pyrazolo[3,4-b]pyridine-5-carbaldehyde; 885223-66-5; 3-Methyl-1H-pyrazolo[3,4-b]pyridine-5-carbaldehyde; 3-Methyl-1H-pyrazolo[3,4-b]pyridin-5-carbaldehyde
EINECS	Contact for details

Quality Control

Our 3-Methyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, including cGMP development and non-GMP research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.