Description

2',3'-Difluoro-3-(1,3-Dioxan-2-Yl)Propiophenone is a high-purity fluorinated organic intermediate with a unique dioxane-protected ketone functionality. This compound is critical for the synthesis of complex molecules, offering chemists a versatile building block for introducing specific fluorinated aromatic motifs. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the creation of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used to develop novel herbicides and pesticides where the difluoro aromatic group enhances biological activity and environmental stability.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored optical or electronic properties.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex molecular architectures via its reactive ketone and protected diol groups.
• Ligand & Catalyst Development: Useful for creating novel fluorinated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2',3'-Difluoro-3-(1,3-Dioxan-2-Yl)Propiophenone
CAS No.	884504-24-9
Molecular Formula	C13H14F2O3
Molecular Weight	256.25 g/mol
Synonyms	1-(2,3-Difluorophenyl)-3-(1,3-dioxan-2-yl)propan-1-one; 3-(1,3-Dioxan-2-yl)-1-(2,3-difluorophenyl)propan-1-one; 2',3'-Difluoro-3-(1,3-dioxan-2-yl)propiophenone; 2,3-Difluoro-β-(1,3-dioxan-2-yl)propiophenone; Propiophenone, 2',3'-difluoro-3-(1,3-dioxan-2-yl)-; 884504-24-9; 2,3-Difluorophenyl 3-(1,3-dioxan-2-yl)propyl ketone
EINECS	Contact for details

Quality Control

Our 2',3'-Difluoro-3-(1,3-Dioxan-2-Yl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.