Description

2-Chloro-5-Fluoro-6-Formylpyridine is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated and formyl-substituted structure makes it an indispensable intermediate for constructing complex molecular architectures with precision. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core for enhanced bioactivity.
• Ligand and Catalyst Development: Serves as a versatile starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its reactive aldehyde group.
• Custom Synthesis and Contract Manufacturing: A fundamental scaffold for custom chemical synthesis services, enabling the production of bespoke compounds for R&D and scale-up.

Basic Information

Product Name	2-Chloro-5-Fluoro-6-Formylpyridine
CAS No.	884494-77-3
Molecular Formula	C6H3ClFNO
Molecular Weight	159.55 g/mol
Synonyms	6-Formyl-2-chloro-5-fluoropyridine; 2-Chloro-5-fluoropyridine-6-carboxaldehyde; 5-Fluoro-2-chloropyridine-6-carbaldehyde; 2-Chloro-5-fluoro-6-pyridinecarboxaldehyde; 2-Chloro-5-fluoropyridine-6-carbaldehyde; 6-Aldehyde-2-chloro-5-fluoropyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Fluoro-6-Formylpyridine is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, GC, and NMR analysis, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon to preserve stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.