Description

2,2-Dimethylpropane-1,3-Diyl [2-Bromophenyl] Boronate is a specialized organoboron compound, specifically a neopentyl glycol-derived boronic ester. This chemical matters as a versatile and stable synthetic intermediate, crucial for modern cross-coupling reactions like the Suzuki-Miyaura coupling, which are foundational to pharmaceutical and advanced materials research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific biphenyl structures.
• Material Science: Serves as a precursor for organic light-emitting diodes (OLEDs) and other electronic materials where controlled conjugation is essential.
• Chemical Research: A valuable reagent in academic and industrial laboratories for methodology development and exploring new C-C bond formation strategies.
• Ligand & Catalyst Preparation: Can be utilized to synthesize sophisticated ligands or be incorporated into metal-organic frameworks (MOFs) and catalysts.
• Fine Chemical Production: Enables the precise introduction of the 2-bromophenyl moiety into complex molecules for specialty chemical manufacturing.

Basic Information

Product Name	2,2-Dimethylpropane-1,3-Diyl [2-Bromophenyl] Boronate
CAS No.	884010-16-6
Molecular Formula	C13H18BBrO2
Molecular Weight	297.00 g/mol
Synonyms	2-Bromophenylboronic acid neopentyl glycol ester; (2-Bromophenyl)boronic acid 2,2-dimethyl-1,3-propanediol ester; Neopentyl glycol (2-bromophenyl)boronate; 2,2-Dimethyl-1,3-propanediol (2-bromophenyl)boronate; 2-Bromophenyl-B-neopentyl glycolato borane; B-(2-Bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (common structural analog name); 2-Bromophenylboronic ester; 884010-16-6
EINECS	Contact for details

Quality Control

Our 2,2-Dimethylpropane-1,3-Diyl [2-Bromophenyl] Boronate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality systems support compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.