Description

3-Bromo-2-Cyanophenylboronic Acid Neopentyl Glycol Ester is a high-purity, protected boronic acid derivative essential for advanced organic synthesis. This compound matters as a critical, air-stable building block for constructing complex molecules via cross-coupling reactions, offering superior handling characteristics compared to its free acid form. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those containing biaryl or heterobiaryl scaffolds.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its stability for efficient scale-up.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs or organic semiconductors.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for diagnostic and research applications.
• Catalyst Ligand Preparation: Can be utilized to synthesize novel ligands for transition metal catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A vital reagent for CROs and CDMOs offering bespoke chemical synthesis services to global clients.

Basic Information

Product Name	3-Bromo-2-Cyanophenylboronic Acid Neopentyl Glycol Ester
CAS No.	883899-07-8
Molecular Formula	C₁₄H₁₇BBrNO₂
Molecular Weight	322.01 g/mol
Synonyms	2-Cyano-3-bromophenylboronic acid neopentyl glycol ester; (3-Bromo-2-cyanophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Bromo-2-cyanobenzeneboronic acid pinacol ester; B-(3-Bromo-2-cyanophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 883899-07-8; Boronic acid, B-(3-bromo-2-cyanophenyl)-, 1,1-dimethylethyl ester; 3-Bromo-2-cyanophenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Cyanophenylboronic Acid Neopentyl Glycol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance in cGMP and ISO environments for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed under an inert atmosphere to maximize long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.