Description

3-Chloro-2-Cyanophenylboronic Acid Neopentyl Glycol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound matters as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key arylboron reagent for forming carbon-carbon bonds in complex molecule synthesis.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Serves as a precursor in creating novel herbicides, fungicides, and insecticides with improved efficacy.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: A building block for organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	3-Chloro-2-Cyanophenylboronic Acid Neopentyl Glycol Ester
CAS No.	883899-06-7
Molecular Formula	C₁₄H₁₇BClNO₃
Molecular Weight	293.55 g/mol
Synonyms	3-Chloro-2-cyanobenzeneboronic acid neopentyl glycol ester; (3-Chloro-2-cyanophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; 3-Chloro-2-cyanophenylboronic acid pinacol ester (common misnomer); B-(3-Chloro-2-cyanophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-Cyano-6-chlorophenylboronic acid neopentyl glycol ester; Boronic acid, B-(3-chloro-2-cyanophenyl)-, 1,1-dimethylethyl ester (related); 883899-06-7
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Cyanophenylboronic Acid Neopentyl Glycol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.