Description

2-Cyano-3-Methoxyphenylboronic Acid Neopentyl Glycol Ester is a protected boronic acid derivative, a crucial intermediate in modern synthetic chemistry. Its primary value lies in its enhanced stability compared to the free boronic acid, making it ideal for complex multi-step synthesis where standard boronate esters might be susceptible to hydrolysis. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for Suzuki-Miyaura cross-coupling reactions used to construct complex biaryl and heterobiaryl scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing complex aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific biaryl structures.
• Material Science Research: Serves as a monomer or precursor in the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the creation of novel palladium ligands and other organometallic catalysts for cross-coupling chemistry.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical reagent for fine chemical and custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Cyano-3-Methoxyphenylboronic Acid Neopentyl Glycol Ester
CAS No.	883899-02-3
Molecular Formula	C14H18BNO4
Molecular Weight	275.11 g/mol
Synonyms	(2-Cyano-3-methoxyphenyl)boronic acid neopentyl glycol ester; 2-Methoxy-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; 2-Cyano-3-methoxybenzeneboronic acid neopentyl glycol ester; 2-Methoxy-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; B-(2-Cyano-3-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (2-cyano-3-methoxyphenyl)boronate; CAS 883899-02-3
EINECS	Contact for details

Quality Control

Every batch of our 2-Cyano-3-Methoxyphenylboronic Acid Neopentyl Glycol Ester is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency. Our products undergo rigorous quality testing, including advanced chromatographic analysis, to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.