Description

3-(4-Methyl-1-Piperazinylmethyl)Benzeneboronic Acid Pinacol Ester, 97% is a high-purity, protected boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in providing a stable, reactive handle for Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing aryl-aryl bonds.
• Suzuki-Miyaura Cross-Coupling Reagent: Used as a stable boronic ester partner for palladium-catalyzed carbon-carbon bond formation with aryl/vinyl halides or triflates.
• Drug Discovery & Medicinal Chemistry: Enables the rapid construction and diversification of chemical libraries for biological screening and structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Intermediate in the production of advanced crop protection agents and herbicides.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel ligands or functionalized materials.
• Material Science Research: Building block for creating organic electronic materials, polymers, and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-(4-Methyl-1-Piperazinylmethyl)Benzeneboronic Acid Pinacol Ester, 97%
CAS No.	883738-27-0
Molecular Formula	C19H31BN2O2
Molecular Weight	330.28 g/mol
Synonyms	[4-(4-Methylpiperazin-1-ylmethyl)phenyl]boronic acid pinacol ester; 3-(4-Methylpiperazin-1-ylmethyl)phenylboronic acid pinacol ester; (3-((4-Methylpiperazin-1-yl)methyl)phenyl)boronic acid pinacol ester; B-[3-[(4-Methyl-1-piperazinyl)methyl]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-[(4-Methylpiperazin-1-yl)methyl]benzeneboronic acid pinacol ester; Boronic acid, B-[3-[(4-methyl-1-piperazinyl)methyl]phenyl]-, 1,1-dimethylethyl ester; 883738-27-0; Pinacol 3-((4-methylpiperazin-1-yl)methyl)phenylboronate
EINECS	Contact for details

Quality Control

Our 3-(4-Methyl-1-Piperazinylmethyl)Benzeneboronic Acid Pinacol Ester is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure the 97% minimum purity and identity are met. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency, supporting your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.