Description

4,4,5,5-Tetramethyl-2-(2-Methyl-4-Nitrophenyl)-1,3,2-Dioxaborolane is a high-value, synthetically versatile organoboron building block. This compound matters for its role as a key intermediate in modern cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific substituted aromatic structures.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Employed in the synthesis of tagged molecules and bioconjugates for diagnostic and research applications.
• Academic & Industrial R&D: A valuable reagent for methodological development in synthetic organic chemistry and catalysis studies.
• Fine Chemical Production: Used in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(2-Methyl-4-Nitrophenyl)-1,3,2-Dioxaborolane
CAS No.	883715-40-0
Molecular Formula	C₁₄H₂₀BNO₄
Molecular Weight	277.13 g/mol
Synonyms	2-Methyl-4-nitrophenylboronic acid pinacol ester; (2-Methyl-4-nitrophenyl)boronic acid pinacol ester; 2-(2-Methyl-4-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-Methyl-4-nitrobenzeneboronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-(2-methyl-4-nitrophenyl)-1,3,2-dioxaborolane; 2-Methyl-4-nitrophenyl-Bpin; B-(2-Methyl-4-nitrophenyl)pinacolborane
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(2-Methyl-4-Nitrophenyl)-1,3,2-Dioxaborolane is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific R&D or cGMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (NMR)	≥95.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.