Description

2-Bromo-5-Chloro-1,3-Difluorobenzene is a high-purity, multi-halogenated benzene derivative serving as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it an invaluable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the halogen atoms contribute to biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic materials, enhancing charge transport and thermal stability.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for synthesizing specialty polymers with unique flame-retardant or dielectric properties.
• Chemical Research & Development: Employed in academic and industrial labs for methodology development, such as cross-coupling reactions and nucleophilic aromatic substitution.
• Dye & Pigment Intermediates: Used in the synthesis of complex halogenated dyes and pigments for high-performance applications.

Basic Information

Product Name	2-Bromo-5-Chloro-1,3-Difluorobenzene
CAS No.	883546-16-5
Molecular Formula	C6H2BrClF2
Molecular Weight	227.44 g/mol
Synonyms	1-Bromo-4-chloro-2,6-difluorobenzene; 2,6-Difluoro-4-chlorobromobenzene; 4-Chloro-2,6-difluorobromobenzene; Benzene, 2-bromo-5-chloro-1,3-difluoro-; 5-Chloro-2-bromo-1,3-difluorobenzene; 2-Bromo-5-chloro-1,3-difluoro-benzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Chloro-1,3-Difluorobenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent lot-to-lot quality. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.